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Perinatal murine cytomegalovirus infection reshapes the transcriptional profile and functionality of NK cells

Infections in early life can elicit substantially different immune responses and pathogenesis than infections in adulthood. Here, we investigate the consequences of murine cytomegalovirus infection in newborn mice on NK cells. We show that infection severely compromised NK cell maturation and functi...

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Detalles Bibliográficos
Autores principales: Rožmanić, Carmen, Lisnić, Berislav, Pribanić Matešić, Marina, Mihalić, Andrea, Hiršl, Lea, Park, Eugene, Lesac Brizić, Ana, Indenbirken, Daniela, Viduka, Ina, Šantić, Marina, Adler, Barbara, Yokoyama, Wayne M., Krmpotić, Astrid, Juranić Lisnić, Vanda, Jonjić, Stipan, Brizić, Ilija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570381/
https://www.ncbi.nlm.nih.gov/pubmed/37828009
http://dx.doi.org/10.1038/s41467-023-42182-w