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Chronic application of alcohol-soluble gluten extract over undamaged skin causes clinical sensitization for life-threatening anaphylaxis via activation of systemic Th2 immune responses in mice

INTRODUCTION: Gluten allergy is a major public health problem that is growing at an alarming rate. Specific mechanisms underlying sensitization to gluten remain incompletely understood. Currently, it is unclear whether chronic exposure to alcohol-soluble gluten extract via undamaged skin has the cap...

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Detalles Bibliográficos
Autores principales: Jorgensen, Rick, Gao, Haoran, Chandra, Shivam, Sundar, Vaisheswini, Loy, Jaden, Van Antwerp, Chris, Ng, Perry K. W., Gangur, Venu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570422/
https://www.ncbi.nlm.nih.gov/pubmed/37841051
http://dx.doi.org/10.3389/falgy.2023.1214051