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Leukemic conversion involving RAS mutations of type 1 CALR-mutated primary myelofibrosis in a patient treated for HCV cirrhosis: a case report

Somatic frameshift mutations in exon 9 of calreticulin (CALR) gene are recognized as disease drivers in primary myelofibrosis (PMF), one of the three classical Philadelphia-negative myeloproliferative neoplasms (MPNs). Type 1/type 1-like CALR mutations particularly confer a favorable prognostic and...

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Detalles Bibliográficos
Autores principales: Gurban, Petruta, Mambet, Cristina, Botezatu, Anca, Necula, Laura G., Neagu, Ana I., Matei, Lilia, Pitica, Ioana M., Nedeianu, Saviana, Chivu-Economescu, Mihaela, Bleotu, Coralia, Ataman, Marius, Mocanu, Gabriela, Saguna, Carmen, Pavel, Anca G., Stambouli, Danae, Sepulchre, Elise, Anton, Gabriela, Diaconu, Carmen C., Constantinescu, Stefan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570518/
https://www.ncbi.nlm.nih.gov/pubmed/37841434
http://dx.doi.org/10.3389/fonc.2023.1266996