SARS-CoV-2 mutations affect antigen processing by the proteasome to alter CD8(+) T cell responses

Mutations within viral epitopes can result in escape from T cells, but the contribution of mutations in flanking regions of epitopes in SARS-CoV-2 has not been investigated. Focusing on two SARS-CoV-2 nucleoprotein CD8(+) epitopes, we investigated the contribution of these flanking mutations to prot...

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Detalles Bibliográficos
Autores principales: Wellington, Dannielle, Yin, Zixi, Yu, Zhanru, Heilig, Raphael, Davis, Simon, Fischer, Roman, Felce, Suet Ling, Antoun, Elie, Hublitz, Philip, Beveridge, Ryan, Dong, Danning, Liu, Guihai, Yao, Xuan, Peng, Yanchun, Kessler, Benedikt M., Dong, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570596/
https://www.ncbi.nlm.nih.gov/pubmed/37842619
http://dx.doi.org/10.1016/j.heliyon.2023.e20076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570596/
https://www.ncbi.nlm.nih.gov/pubmed/37842619
http://dx.doi.org/10.1016/j.heliyon.2023.e20076

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