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Interplay between BMP2 and Notch signaling in endothelial-mesenchymal transition: implications for cardiac fibrosis

BACKGROUND: The endothelial-to-mesenchymal transition (EndoMT) is a crucial process in cardiovascular development and disorders. Cardiac fibrosis, characterized by excessive collagen deposition, occurs in heart failure, leading to the organ remodeling. Embryonic signaling pathways such as bone morph...

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Detalles Bibliográficos
Autores principales: Docshin, Pavel, Bairqdar, Ahmad, Malashicheva, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570623/
https://www.ncbi.nlm.nih.gov/pubmed/37842185
http://dx.doi.org/10.21037/sci-2023-019