Targeting KRAS for the potential treatment of pancreatic ductal adenocarcinoma: Recent advancements provide hope (Review)

Kirsten rat sarcoma viral oncogene homolog (KRAS) is one of the most frequently mutated oncogenes in solid tumors. More than 90% of pancreatic ductal adenocarcinoma (PDAC) are driven by mutations in the KRAS gene, suggesting the importance of targeting this oncogene in PDAC. Initial efforts to targe...

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Detalles Bibliográficos
Autores principales: Zhang, Joshua, Darman, Lily, Hassan, Md Sazzad, Von Holzen, Urs, Awasthi, Niranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570661/
https://www.ncbi.nlm.nih.gov/pubmed/37800636
http://dx.doi.org/10.3892/or.2023.8643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570661/
https://www.ncbi.nlm.nih.gov/pubmed/37800636
http://dx.doi.org/10.3892/or.2023.8643

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