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Targeting KRAS for the potential treatment of pancreatic ductal adenocarcinoma: Recent advancements provide hope (Review)
Kirsten rat sarcoma viral oncogene homolog (KRAS) is one of the most frequently mutated oncogenes in solid tumors. More than 90% of pancreatic ductal adenocarcinoma (PDAC) are driven by mutations in the KRAS gene, suggesting the importance of targeting this oncogene in PDAC. Initial efforts to targe...
Autores principales: | Zhang, Joshua, Darman, Lily, Hassan, Md Sazzad, Von Holzen, Urs, Awasthi, Niranjan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570661/ https://www.ncbi.nlm.nih.gov/pubmed/37800636 http://dx.doi.org/10.3892/or.2023.8643 |
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