Identifying lupus Patient Subsets Through Immune Cell Deconvolution of Gene Expression Data in Two Atacicept Phase II Studies

OBJECTIVE: To use cell‐based gene signatures to identify patients with systemic lupus erythematous (SLE) in the phase II/III APRIL–SLE and phase IIb ADDRESS II trials most likely to respond to atacicept. METHODS: A published immune cell deconvolution algorithm based on Affymetrix gene array data was...

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Detalles Bibliográficos
Autores principales: Studham, Matthew, Vazquez‐Mateo, Cristina, Samy, Eileen, Haselmayer, Philipp, Aydemir, Aida, Rolfe, P. Alexander, Merrill, Joan T., Morand, Eric F., DeMartino, Julie, Kao, Amy, Townsend, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570667/
https://www.ncbi.nlm.nih.gov/pubmed/37710418
http://dx.doi.org/10.1002/acr2.11594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570667/
https://www.ncbi.nlm.nih.gov/pubmed/37710418
http://dx.doi.org/10.1002/acr2.11594

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