Diagnostic Performance of a Tumor Marker Gene Test to Personalize Serum CA19–9 Reference Ranges

PURPOSE: CA19–9 synthesis is influenced by common variants in the fucosyltransferase (FUT) enzymes FUT3 and FUT2. We developed a clinical test to detect FUT variants, and evaluated its diagnostic performance for pancreatic ductal adenocarcinoma (PDAC). EXPERIMENTAL DESIGN: A representative set of co...

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Detalles Bibliográficos
Autores principales: Dbouk, Mohamad, Abe, Toshiya, Koi, Chiho, Ando, Yohei, Saba, Helena, Abou Diwan, Elizabeth, MacGregor-Das, Anne, Blackford, Amanda L., Mocci, Evelina, Beierl, Katie, Dbouk, Ali, He, Jin, Burkhart, Richard, Lennon, Anne Marie, Sokoll, Lori, Canto, Marcia Irene, Eshleman, James R., Goggins, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Precision Medicine and Imaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570677/
https://www.ncbi.nlm.nih.gov/pubmed/37566230
http://dx.doi.org/10.1158/1078-0432.CCR-23-0655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570677/
https://www.ncbi.nlm.nih.gov/pubmed/37566230
http://dx.doi.org/10.1158/1078-0432.CCR-23-0655

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