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Diagnostic Performance of a Tumor Marker Gene Test to Personalize Serum CA19–9 Reference Ranges

PURPOSE: CA19–9 synthesis is influenced by common variants in the fucosyltransferase (FUT) enzymes FUT3 and FUT2. We developed a clinical test to detect FUT variants, and evaluated its diagnostic performance for pancreatic ductal adenocarcinoma (PDAC). EXPERIMENTAL DESIGN: A representative set of co...

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Detalles Bibliográficos
Autores principales:	Dbouk, Mohamad, Abe, Toshiya, Koi, Chiho, Ando, Yohei, Saba, Helena, Abou Diwan, Elizabeth, MacGregor-Das, Anne, Blackford, Amanda L., Mocci, Evelina, Beierl, Katie, Dbouk, Ali, He, Jin, Burkhart, Richard, Lennon, Anne Marie, Sokoll, Lori, Canto, Marcia Irene, Eshleman, James R., Goggins, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Precision Medicine and Imaging
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570677/ https://www.ncbi.nlm.nih.gov/pubmed/37566230 http://dx.doi.org/10.1158/1078-0432.CCR-23-0655

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