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Specific IgG glycosylation differences precede relapse in PR3-ANCA associated vasculitis patients with and without ANCA rise

INTRODUCTION: Immunoglobulin G (IgG) contains a conserved N-glycan in the fragment crystallizable (Fc), modulating its structure and effector functions. In anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) alterations of IgG Fc-glycosylation have been observed to correlate with...

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Detalles Bibliográficos
Autores principales: Wojcik, Iwona, Wuhrer, Manfred, Heeringa, Peter, Stegeman, Coen A., Rutgers, Abraham, Falck, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570725/
https://www.ncbi.nlm.nih.gov/pubmed/37841251
http://dx.doi.org/10.3389/fimmu.2023.1214945