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Teriflunomide and Epstein–Barr virus in a Spanish multiple sclerosis cohort: in vivo antiviral activity and clinical response

BACKGROUND: Epstein–Barr virus (EBV) and human herpesvirus 6 (HHV-6) have been associated with multiple sclerosis (MS). Teriflunomide is an oral disease-modifying therapy approved for treatment of relapsing forms of MS. In the preclinical Theiler’s murine encephalitis virus model of MS, the drug dem...

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Detalles Bibliográficos
Autores principales: Domínguez-Mozo, María Inmaculada, González-Suárez, Inés, Villar, Luisa María, Costa-Frossard, Lucienne, Villarrubia, Noelia, Aladro, Yolanda, Pilo, Belén, Montalbán, Xavier, Comabella, Manuel, Casanova-Peño, Ignacio, Martínez-Ginés, María Luisa, García-Domínguez, Jose Manuel, García-Martínez, María Ángel, Arroyo, Rafael, Álvarez-Lafuente, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570817/
https://www.ncbi.nlm.nih.gov/pubmed/37841253
http://dx.doi.org/10.3389/fimmu.2023.1248182