An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules

Snakebite envenoming is a neglected tropical disease that causes over 100,000 deaths annually. Envenomings result in variable pathologies, but systemic neurotoxicity is among the most serious and is currently only treated with difficult to access and variably efficacious commercial antivenoms. Venom...

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Detalles Bibliográficos
Autores principales: Patel, Rohit N., Clare, Rachel H., Ledsgaard, Line, Nys, Mieke, Kool, Jeroen, Laustsen, Andreas H., Ulens, Chris, Casewell, Nicholas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570928/
https://www.ncbi.nlm.nih.gov/pubmed/37604290
http://dx.doi.org/10.1016/j.bcp.2023.115758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570928/
https://www.ncbi.nlm.nih.gov/pubmed/37604290
http://dx.doi.org/10.1016/j.bcp.2023.115758

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