Cargando…

Rho family small GTPase Rif regulates Wnt5a-Ror1-Dvl2 signaling and promotes lung adenocarcinoma progression

Rho in filopodia (Rif), a member of the Rho family of small GTPases, induces filopodia formation primarily on the dorsal surface of cells; however, its function remains largely unclear. Here, we show that Rif interacts with Ror1, a receptor for Wnt5a that can also induce dorsal filopodia. Our immuno...

Descripción completa

Detalles Bibliográficos
Autores principales: Nishita, Michiru, Kamizaki, Koki, Hoshi, Kyoka, Aruga, Kana, Nishikaku, Ikumi, Shibuya, Hiroshi, Matsumoto, Kunio, Minami, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570955/
https://www.ncbi.nlm.nih.gov/pubmed/37703992
http://dx.doi.org/10.1016/j.jbc.2023.105248