Peripheral blood lymphopenia in sarcoidosis associates with HLA-DRB1 alleles but not with lung immune cells and organ involvement

Different human leukocyte antigen (HLA) alleles associate with disease phenotypes in sarcoidosis. Peripheral blood (PB) lymphopenia is reported as more common in sarcoidosis patients with worse prognosis. The mechanisms behind are unrecognized but a PB depletion due to lymphocytes migrating to lung...

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Detalles Bibliográficos
Autores principales: Darlington, Pernilla, Melin, Jonas, Rivera, Natalia, Grunewald, Johan, Eklund, Anders, Kullberg, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Inflammation/Inflammatory Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570991/
https://www.ncbi.nlm.nih.gov/pubmed/37161980
http://dx.doi.org/10.1093/cei/uxad052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570991/
https://www.ncbi.nlm.nih.gov/pubmed/37161980
http://dx.doi.org/10.1093/cei/uxad052

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