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CRISPR-Cas9 delivery strategies with engineered extracellular vesicles

Therapeutic genome editing has the potential to cure diseases by directly correcting genetic mutations in tissues and cells. Recent progress in the CRISPR-Cas9 systems has led to breakthroughs in gene editing tools because of its high orthogonality, versatility, and efficiency. However, its safe and...

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Detalles Bibliográficos
Autores principales: Lu, Yaoyao, Godbout, Kelly, Lamothe, Gabriel, Tremblay, Jacques P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571031/
https://www.ncbi.nlm.nih.gov/pubmed/37842166
http://dx.doi.org/10.1016/j.omtn.2023.102040