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The multidrug resistance transporter P-glycoprotein confers resistance to ferroptosis inducers

Aim: Ferroptosis is a non-apoptotic form of cell death caused by lethal lipid peroxidation. Several small molecule ferroptosis inducers (FINs) have been reported, yet little information is available regarding their interaction with the ATP-binding cassette (ABC) transporters P-glycoprotein (P-gp, AB...

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Detalles Bibliográficos
Autores principales: Frye, William J. E., Huff, Lyn M., González Dalmasy, José M., Salazar, Paula, Carter, Rachel M., Gensler, Ryan T., Esposito, Dominic, Robey, Robert W., Ambudkar, Suresh V., Gottesman, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571053/
https://www.ncbi.nlm.nih.gov/pubmed/37840856
http://dx.doi.org/10.20517/cdr.2023.29