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The multidrug resistance transporter P-glycoprotein confers resistance to ferroptosis inducers
Aim: Ferroptosis is a non-apoptotic form of cell death caused by lethal lipid peroxidation. Several small molecule ferroptosis inducers (FINs) have been reported, yet little information is available regarding their interaction with the ATP-binding cassette (ABC) transporters P-glycoprotein (P-gp, AB...
Autores principales: | Frye, William J. E., Huff, Lyn M., González Dalmasy, José M., Salazar, Paula, Carter, Rachel M., Gensler, Ryan T., Esposito, Dominic, Robey, Robert W., Ambudkar, Suresh V., Gottesman, Michael M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
OAE Publishing Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571053/ https://www.ncbi.nlm.nih.gov/pubmed/37840856 http://dx.doi.org/10.20517/cdr.2023.29 |
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