Targeting metabolic vulnerabilities to overcome resistance to therapy in acute myeloid leukemia

Malignant hematopoietic cells gain metabolic plasticity, reorganize anabolic mechanisms to improve anabolic output and prevent oxidative damage, and bypass cell cycle checkpoints, eventually outcompeting normal hematopoietic cells. Current therapeutic strategies of acute myeloid leukemia (AML) are b...

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Detalles Bibliográficos
Autores principales: Sharma, Priyanka, Borthakur, Gautam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571063/
https://www.ncbi.nlm.nih.gov/pubmed/37842232
http://dx.doi.org/10.20517/cdr.2023.12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571063/
https://www.ncbi.nlm.nih.gov/pubmed/37842232
http://dx.doi.org/10.20517/cdr.2023.12

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