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MCCC2 is a novel mediator between mitochondria and telomere and functions as an oncogene in colorectal cancer

BACKGROUND: The mitochondrial gene MCCC2, a subunit of the heterodimer of 3-methylcrotonyl-CoA carboxylase, plays a pivotal role in catabolism of leucine and isovaleric acid. The molecular mechanisms and prognostic value still need to be explored in the context of specific cancers, including colorec...

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Detalles Bibliográficos
Autores principales: Liu, Wanjun, Chen, Si, Xie, Wenqing, Wang, Qian, Luo, Qianxin, Huang, Minghan, Gu, Minyi, Lan, Ping, Chen, Daici
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571261/
https://www.ncbi.nlm.nih.gov/pubmed/37828426
http://dx.doi.org/10.1186/s11658-023-00487-0