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MCCC2 is a novel mediator between mitochondria and telomere and functions as an oncogene in colorectal cancer
BACKGROUND: The mitochondrial gene MCCC2, a subunit of the heterodimer of 3-methylcrotonyl-CoA carboxylase, plays a pivotal role in catabolism of leucine and isovaleric acid. The molecular mechanisms and prognostic value still need to be explored in the context of specific cancers, including colorec...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571261/ https://www.ncbi.nlm.nih.gov/pubmed/37828426 http://dx.doi.org/10.1186/s11658-023-00487-0 |