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CDC6, a key replication licensing factor, is overexpressed and confers poor prognosis in diffuse large B-cell lymphoma

BACKGROUND: Cell division cycle 6 (CDC6) is a key licensing factor in the assembly of pre-replicative complexes at origins of replication. The role of CDC6 in the pathogenesis of in diffuse larger B-cell lymphoma (DLBCL) remains unknown. We aim to investigate the effects of CDC6 on the proliferation...

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Detalles Bibliográficos
Autores principales: Shen, Mingfang, Zhang, Yunfeng, Tang, Lun, Fu, Qinyan, Zhang, Jiawei, Xu, Yang, Zeng, Hui, Li, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571299/
https://www.ncbi.nlm.nih.gov/pubmed/37833632
http://dx.doi.org/10.1186/s12885-023-11186-6