Activation of BZW1 by CEBPB in macrophages promotes eIF2α phosphorylation-mediated metabolic reprogramming and endoplasmic reticulum stress in MRL/lpr lupus-prone mice

BACKGROUND: Lupus nephritis (LN) is associated with significant mortality and morbidity, while effective therapeutics and biomarkers are limited since the pathogenesis is complex. This study investigated the roles of the CEBPB/BZW1/eIF2α axis in metabolic reprogramming and endoplasmic reticulum stre...

Descripción completa

Detalles Bibliográficos
Autores principales: Qi, Huimeng, Zheng, Zhaoguo, Liu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571419/
https://www.ncbi.nlm.nih.gov/pubmed/37828427
http://dx.doi.org/10.1186/s11658-023-00494-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571419/
https://www.ncbi.nlm.nih.gov/pubmed/37828427
http://dx.doi.org/10.1186/s11658-023-00494-1

Ejemplares similares