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Pan-cancer spatially resolved single-cell analysis reveals the crosstalk between cancer-associated fibroblasts and tumor microenvironment

Cancer-associated fibroblasts (CAFs) are a heterogeneous cell population that plays a crucial role in remodeling the tumor microenvironment (TME). Here, through the integrated analysis of spatial and single-cell transcriptomics data across six common cancer types, we identified four distinct functio...

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Detalles Bibliográficos
Autores principales: Ma, Chenxi, Yang, Chengzhe, Peng, Ai, Sun, Tianyong, Ji, Xiaoli, Mi, Jun, Wei, Li, Shen, Song, Feng, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571470/
https://www.ncbi.nlm.nih.gov/pubmed/37833788
http://dx.doi.org/10.1186/s12943-023-01876-x