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Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation

BACKGROUND: Testosterone contributes to male organism development, such as bone density, muscle development, and fat repartition. Estrogen (derived from testosterone) also contributes to female reproductive system development. Here, we investigated the effect of testosterone on glioma cells and brai...

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Detalles Bibliográficos
Autores principales: Kanwore, Kouminin, Kanwore, Konimpo, Guo, Xiaoxiao, Xia, Ying, Zhou, Han, Zhang, Lin, Adzika, Gabriel Komla, Joseph, Adu-Amankwaah, Abiola, Ayanlaja Abdulrahman, Mu, Peipei, Kambey, Piniel Alphayo, Noah, Marie Louis N’dzie, Gao, DianShuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571473/
https://www.ncbi.nlm.nih.gov/pubmed/37833789
http://dx.doi.org/10.1186/s41232-023-00300-7