Multifaceted functions of Drp1 in hypoxia/ischemia-induced mitochondrial quality imbalance: from regulatory mechanism to targeted therapeutic strategy

Hypoxic-ischemic injury is a common pathological dysfunction in clinical settings. Mitochondria are sensitive organelles that are readily damaged following ischemia and hypoxia. Dynamin-related protein 1 (Drp1) regulates mitochondrial quality and cellular functions via its oligomeric changes and mul...

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Detalles Bibliográficos
Autores principales: Hao, Shuai, Huang, He, Ma, Rui-Yan, Zeng, Xue, Duan, Chen-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571487/
https://www.ncbi.nlm.nih.gov/pubmed/37833768
http://dx.doi.org/10.1186/s40779-023-00482-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571487/
https://www.ncbi.nlm.nih.gov/pubmed/37833768
http://dx.doi.org/10.1186/s40779-023-00482-8

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