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Multifaceted functions of Drp1 in hypoxia/ischemia-induced mitochondrial quality imbalance: from regulatory mechanism to targeted therapeutic strategy
Hypoxic-ischemic injury is a common pathological dysfunction in clinical settings. Mitochondria are sensitive organelles that are readily damaged following ischemia and hypoxia. Dynamin-related protein 1 (Drp1) regulates mitochondrial quality and cellular functions via its oligomeric changes and mul...
Autores principales: | Hao, Shuai, Huang, He, Ma, Rui-Yan, Zeng, Xue, Duan, Chen-Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571487/ https://www.ncbi.nlm.nih.gov/pubmed/37833768 http://dx.doi.org/10.1186/s40779-023-00482-8 |
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