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Activation of UBEC2 by transcription factor MYBL2 affects DNA damage and promotes gastric cancer progression and cisplatin resistance

Ubiquitin-conjugating enzyme E2 C (UBE2C) plays a carcinogenic role in gastric cancer (GC); yet, its role in cisplatin (DDP) resistance in GC is enigmatic. This study sought to probe into the impact of UBE2C on DDP resistance in GC and its concrete molecular mechanism in GC progression. Bioinformati...

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Detalles Bibliográficos
Autores principales: Long, Jiegen, Zhu, Bin, Tian, Tao, Ren, Linfei, Tao, Yong, Zhu, Haitao, Li, Dengwei, Xu, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571520/
https://www.ncbi.nlm.nih.gov/pubmed/37840753
http://dx.doi.org/10.1515/med-2023-0757