Blockade of IL-10 Signaling Ensures Mifamurtide Efficacy in Metastatic Osteosarcoma

SIMPLE SUMMARY: Osteosarcoma is a highly aggressive and metastasizing primary bone neoplasm with poor patient survival rates. Mifamurtide is an immunostimulant drug whose clinical efficacy is still debated. Here we identified IL-10 as a new possible target useful to improve mifamurtide effectiveness...

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Detalles Bibliográficos
Autores principales: Nastasi, Nicoletta, Pasha, Amada, Bruno, Gennaro, Subbiani, Angela, Pietrovito, Laura, Leo, Angela, Scala, Lucia, de Simone, Lorena, Casazza, Gabriella, Lunardi, Federica, Taddei, Maria Letizia, Tamburini, Angela, Tondo, Annalisa, Favre, Claudio, Calvani, Maura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571595/
https://www.ncbi.nlm.nih.gov/pubmed/37835437
http://dx.doi.org/10.3390/cancers15194744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571595/
https://www.ncbi.nlm.nih.gov/pubmed/37835437
http://dx.doi.org/10.3390/cancers15194744

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