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Vaccine-induced antigen archiving enhances local memory CD8+ T cell responses following an unrelated viral infection

Viral and vaccine antigens persist or are archived in lymph node stromal cells (LNSC) such as lymphatic endothelial cells (LEC) and fibroblastic reticular cells (FRC). Here, we find that, during the time frame of antigen archiving, LEC apoptosis caused by a second, but unrelated, innate immune stimu...

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Detalles Bibliográficos
Autores principales: Tamburini, Beth, Doan, Thu, Forward, Tadg, Lucas, Erin, Fleming, Ira, Uecker-Martin, Aspen, Hesselberth, Jay, Morrison, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571600/
https://www.ncbi.nlm.nih.gov/pubmed/37841845
http://dx.doi.org/10.21203/rs.3.rs-3307809/v1