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The impact of blood MCP-1 levels on Alzheimer’s disease with genetic variation of UNC5C and NAV3 loci

BACKGROUND: Previous study shows that monocyte chemoattractant protein-1 (MCP-1), which is implicated in the peripheral proinflammatory cascade and blood-brain barrier (BBB) disruption, modulates the genetic risks of AD in established AD loci. METHODS: In this study, we hypothesized that blood MCP-1...

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Detalles Bibliográficos
Autores principales: Huang, Jinghan, Wang, Yixuan, Stein, Thor D., Ang, Ting Fang Alvin, Zhu, Yibo, Tao, Qiushan, Lunetta, Kathryn L., Mez, Jesse, Au, Rhoda, Farrer, Lindsay A., Qiu, Wei Qiao, Zhang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571626/
https://www.ncbi.nlm.nih.gov/pubmed/37841863
http://dx.doi.org/10.21203/rs.3.rs-3376348/v1