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TP53 Mutation in Acute Myeloid Leukemia: An Old Foe Revisited

SIMPLE SUMMARY: The TP53 gene encodes the p53 protein, which plays a diverse role in responding to various cellular stresses. p53 consists of several functional domains, including a tetramerization domain for forming heterotetramers and a DNA-binding domain for bindings to p53-responsive elements. T...

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Detalles Bibliográficos
Autor principal: Shin, Dong-Yeop
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571655/
https://www.ncbi.nlm.nih.gov/pubmed/37835510
http://dx.doi.org/10.3390/cancers15194816