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METTL3-mediated m(6)A modification of lncRNA SNHG3 accelerates gastric cancer progression by modulating miR-186-5p/cyclinD2 axis

OBJECTIVES: METTL3 as an m(6)A methyltransferase acts in diverse malignancies including gastric cancer (GC). We aimed to reveal the underlying mechanisms by which METTL3 contributes to gastric carcinogenesis. METHODS: The association of METTL3 and SNHG3 with GC was analyzed by qRT-PCR, Western blot,...

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Detalles Bibliográficos
Autores principales: Ji, Guo, Wang, Xiu, Xi, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571673/
https://www.ncbi.nlm.nih.gov/pubmed/37823387
http://dx.doi.org/10.1177/03946320231204694