PD-L1 Expression by RNA-Sequencing in Non-Small Cell Lung Cancer: Concordance with Immunohistochemistry and Associations with Pembrolizumab Treatment Outcomes

SIMPLE SUMMARY: We compared RNA next-generation sequencing (RNA-seq) to standard immunohistochemistry (IHC) for PD-L1 expression measurement and associations with pembrolizumab immunotherapy outcomes in NSCLC patient tumors. RNA-seq and IHC PD-L1 score interpretation agreed for 80% of patients, and...

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Detalles Bibliográficos
Autores principales: Nesline, Mary K., Previs, Rebecca A., Dy, Grace K., Deng, Lei, Lee, Yong Hee, DePietro, Paul, Zhang, Shengle, Meyers, Nathan, Severson, Eric, Ramkissoon, Shakti, Pabla, Sarabjot, Conroy, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571724/
https://www.ncbi.nlm.nih.gov/pubmed/37835483
http://dx.doi.org/10.3390/cancers15194789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571724/
https://www.ncbi.nlm.nih.gov/pubmed/37835483
http://dx.doi.org/10.3390/cancers15194789

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