Cargando…

The Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Breast Cancer Are Regulated by N-Linked Glycosylation-Dependent Activation of STAT3 and STAT1

PD-L1 has been characterized as an inhibitory immune checkpoint, leading to the suppression of potential anti-tumor immune activities in many cancer types. In view of the relatively limited efficacy of immune checkpoint blockades against PD-L1 in breast cancer, our recent study addressed the possibi...

Descripción completa

Detalles Bibliográficos
Autores principales: Erlichman, Nofar, Meshel, Tsipi, Baram, Tamir, Abu Raiya, Alaa, Horvitz, Tamar, Ben-Yaakov, Hagar, Ben-Baruch, Adit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571791/
https://www.ncbi.nlm.nih.gov/pubmed/37830552
http://dx.doi.org/10.3390/cells12192338