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Association of Chromosome 17 Aneuploidy, TP53 Deletion, Expression and Its rs1042522 Variant with Multiple Myeloma Risk and Response to Thalidomide/Bortezomib Treatment

SIMPLE SUMMARY: The detailed role of the TP53 p.P72R (rs1042522) variant in the etiology and course of multiple myeloma (MM), as well as its association with chromosome 17 aberrations, has not been analyzed in a such a wide range. In our study, we have explored the significance of the p.P72R variant...

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Detalles Bibliográficos
Autores principales: Popek-Marciniec, Sylwia, Styk, Wojciech, Wojcierowska-Litwin, Magdalena, Chocholska, Sylwia, Szudy-Szczyrek, Aneta, Samardakiewicz, Marzena, Swiderska-Kolacz, Grazyna, Czerwik-Marcinkowska, Joanna, Zmorzynski, Szymon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571826/
https://www.ncbi.nlm.nih.gov/pubmed/37835441
http://dx.doi.org/10.3390/cancers15194747