High-Dose Acetaminophen with N-acetylcysteine Rescue Inhibits M2 Polarization of Tumor-Associated Macrophages

SIMPLE SUMMARY: High dose acetaminophen (AAP) with N-acetylcysteine (NAC) rescue has demonstrated promising results in pre-clinical and clinical studies. However, the mechanism is not clearly understood. In the present manuscript, we evaluate the effects of high dose AAP/NAC on the tumor immune micr...

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Detalles Bibliográficos
Autores principales: Bryan, Allyn, Pingali, Pavani, Joslyn, Martha, Li, Howard, Bernas, Tytus, Koblinski, Jennifer, Landry, Joseph, Lee, Won Sok, Patel, Bhaumik, Neuwelt, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571846/
https://www.ncbi.nlm.nih.gov/pubmed/37835464
http://dx.doi.org/10.3390/cancers15194770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571846/
https://www.ncbi.nlm.nih.gov/pubmed/37835464
http://dx.doi.org/10.3390/cancers15194770

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