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Characterization of the Intraclonal Complexity of Chronic Lymphocytic Leukemia B Cells: Potential Influences of B-Cell Receptor Crosstalk with Other Stimuli

SIMPLE SUMMARY: Chronic lymphocytic leukemia (CLL) clones contain cells differing in age: recently born, proliferative (PF), intermediate (IF), and resting (RF) fractions. We used deuterium incorporation into newly synthesized DNA in leukemic cells from patients with CLL to refine the “aging” kineti...

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Detalles Bibliográficos
Autores principales: Mazzarello, Andrea N., Fitch, Mark, Cardillo, Martina, Ng, Anita, Bhuiya, Sabreen, Sharma, Esha, Bagnara, Davide, Kolitz, Jonathan E., Barrientos, Jacqueline C., Allen, Steven L., Rai, Kanti R., Rhodes, Joanna, Hellerstein, Marc K., Chiorazzi, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571896/
https://www.ncbi.nlm.nih.gov/pubmed/37835400
http://dx.doi.org/10.3390/cancers15194706