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NKCC1 and KCC2 Chloride Transporters Have Different Membrane Dynamics on the Surface of Hippocampal Neurons

Na-K-2Cl cotransporter 1 (NKCC1) regulates chloride influx in neurons and thereby GABA(A) receptor activity in normal and pathological conditions. Here, we characterized in hippocampal neurons the membrane expression, distribution and dynamics of exogenous NKCC1a and NKCC1b isoforms and compared the...

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Detalles Bibliográficos
Autores principales: Pol, Erwan, Côme, Etienne, Merlaud, Zaha, Gouhier, Juliette, Russeau, Marion, Scotto-Lomassese, Sophie, Moutkine, Imane, Marques, Xavier, Lévi, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571912/
https://www.ncbi.nlm.nih.gov/pubmed/37830575
http://dx.doi.org/10.3390/cells12192363