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Stress Keratin 17 Is a Predictive Biomarker Inversely Associated with Response to Immune Check-Point Blockade in Head and Neck Squamous Cell Carcinomas and Beyond

SIMPLE SUMMARY: Between 15 and 35% of head and neck cancer patients respond to immune check-point blockade therapy (ICB), and some may experience potentially life-threatening adverse events. Biomarkers that can reliably predict response to therapy are needed to improve patient selection. Our pilot d...

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Detalles Bibliográficos
Autores principales: Lozar, Taja, Laklouk, Israa, Golfinos, Athena E., Gavrielatou, Niki, Xu, Jin, Flynn, Christopher, Keske, Aysenur, Yu, Menggang, Bruce, Justine Y., Wang, Wei, Grasic Kuhar, Cvetka, Bailey, Howard H., Harari, Paul M., Dinh, Huy Q., Rimm, David L., Hu, Rong, Lambert, Paul F., Fitzpatrick, Megan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571921/
https://www.ncbi.nlm.nih.gov/pubmed/37835599
http://dx.doi.org/10.3390/cancers15194905