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Synergistic Effects of Metformin and Trastuzumab on HER2 Positive Gastroesophageal Adenocarcinoma Cells In Vitro and In Vivo

SIMPLE SUMMARY: Metformin is widely used to treat type 2 diabetes with minimal side effects. Trastuzumab (Tmab) in combination with chemotherapy has been the standard treatment for HER2+ gastric cancer (GC) for the last two decades. Unfortunately, the use of subsequent HER2 targeted agents have not...

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Detalles Bibliográficos
Autores principales: Kim, Jin-Soo, Kim, Mi Young, Hong, Sungyoul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571931/
https://www.ncbi.nlm.nih.gov/pubmed/37835462
http://dx.doi.org/10.3390/cancers15194768