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DNA Hypomethylation in the TNF-Alpha Gene Predicts Rheumatoid Arthritis Classification in Patients with Early Inflammatory Symptoms

Biomarkers for the classification of rheumatoid arthritis (RA), and particularly for anti-citrullinated peptide antibody (ACPA)-negative patients, remain an important hurdle for the early initiation of treatment. Taking advantage of DNA-methylation patterns specific to early RA, quantitative methyla...

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Detalles Bibliográficos
Autores principales: Pitaksalee, Rujiraporn, Parmar, Rekha, Hodgett, Richard, Emery, Paul, Ponchel, Frederique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571942/
https://www.ncbi.nlm.nih.gov/pubmed/37830590
http://dx.doi.org/10.3390/cells12192376