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DNA Hypomethylation in the TNF-Alpha Gene Predicts Rheumatoid Arthritis Classification in Patients with Early Inflammatory Symptoms
Biomarkers for the classification of rheumatoid arthritis (RA), and particularly for anti-citrullinated peptide antibody (ACPA)-negative patients, remain an important hurdle for the early initiation of treatment. Taking advantage of DNA-methylation patterns specific to early RA, quantitative methyla...
Autores principales: | Pitaksalee, Rujiraporn, Parmar, Rekha, Hodgett, Richard, Emery, Paul, Ponchel, Frederique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10571942/ https://www.ncbi.nlm.nih.gov/pubmed/37830590 http://dx.doi.org/10.3390/cells12192376 |
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