New JAK3-INSL3 Fusion Transcript—An Oncogenic Event in Cutaneous T-Cell Lymphoma

Constitutively activated tyrosine kinase JAK3 is implicated in the pathogenesis of cutaneous T-cell lymphomas (CTCL). The mechanisms of constitutive JAK3 activation are unknown although a JAK3 mutation was reported in a small portion of CTCL patients. In this study, we assessed the oncogenic roles o...

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Detalles Bibliográficos
Autores principales: Velatooru, Loka Reddy, Hu, Cheng Hui, Bijani, Pedram, Wang, Xiaohong, Bojaxhi, Pierr, Chen, Hao, Duvic, Madeleine, Ni, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572011/
https://www.ncbi.nlm.nih.gov/pubmed/37830594
http://dx.doi.org/10.3390/cells12192381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572011/
https://www.ncbi.nlm.nih.gov/pubmed/37830594
http://dx.doi.org/10.3390/cells12192381

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