Kidney-Specific Membrane-Bound Serine Proteases CAP1/Prss8 and CAP3/St14 Affect ENaC Subunit Abundances but Not Its Activity

The serine proteases CAP1/Prss8 and CAP3/St14 are identified as ENaC channel-activating proteases in vitro, highly suggesting that they are required for proteolytic activation of ENaC in vivo. The present study tested whether CAP3/St14 is relevant for renal proteolytic ENaC activation and affects EN...

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Detalles Bibliográficos
Autores principales: Ehret, Elodie, Stroh, Sévan, Auberson, Muriel, Ino, Frédérique, Jäger, Yannick, Maillard, Marc, Szabo, Roman, Bugge, Thomas H., Frateschi, Simona, Hummler, Edith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572026/
https://www.ncbi.nlm.nih.gov/pubmed/37830556
http://dx.doi.org/10.3390/cells12192342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572026/
https://www.ncbi.nlm.nih.gov/pubmed/37830556
http://dx.doi.org/10.3390/cells12192342

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