Cargando…
Kidney-Specific Membrane-Bound Serine Proteases CAP1/Prss8 and CAP3/St14 Affect ENaC Subunit Abundances but Not Its Activity
The serine proteases CAP1/Prss8 and CAP3/St14 are identified as ENaC channel-activating proteases in vitro, highly suggesting that they are required for proteolytic activation of ENaC in vivo. The present study tested whether CAP3/St14 is relevant for renal proteolytic ENaC activation and affects EN...
Autores principales: | Ehret, Elodie, Stroh, Sévan, Auberson, Muriel, Ino, Frédérique, Jäger, Yannick, Maillard, Marc, Szabo, Roman, Bugge, Thomas H., Frateschi, Simona, Hummler, Edith |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572026/ https://www.ncbi.nlm.nih.gov/pubmed/37830556 http://dx.doi.org/10.3390/cells12192342 |
Ejemplares similares
-
Kidney-Specific CAP1/Prss8-Deficient Mice Maintain ENaC-Mediated Sodium Balance through an Aldosterone Independent Pathway
por: Ehret, Elodie, et al.
Publicado: (2022) -
The epidermal barrier function is dependent on the serine protease CAP1/Prss8
por: Leyvraz, Céline, et al.
Publicado: (2005) -
Synergistic Activation of ENaC by Three Membrane-bound Channel-activating Serine Proteases (mCAP1, mCAP2, and mCAP3) and Serum- and Glucocorticoid-regulated Kinase (Sgk1) in Xenopus Oocytes
por: Vuagniaux, Grégoire, et al.
Publicado: (2002) -
The Channel-Activating Protease CAP1/Prss8 Is Required for Placental Labyrinth Maturation
por: Hummler, Edith, et al.
Publicado: (2013) -
ENaC activation by proteases
por: Anand, Deepika, et al.
Publicado: (2022)