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Mimicry of microbially-derived butyrate reveals templates for potent intestinal epithelial HIF stabilizers
Microbiota-derived short-chain fatty acids, including butyrate (BA), have multiple beneficial health effects. In the colon, BA concentrations range from 10 to 20 mM and up to 95% is utilized as energy by the mucosa. BA plays a key role in epithelial-barrier regulation and anti-inflammation, and regu...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572066/ https://www.ncbi.nlm.nih.gov/pubmed/37822087 http://dx.doi.org/10.1080/19490976.2023.2267706 |