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Molecular Basis and Natural History of Medullary Thyroid Cancer: It is (Almost) All in the RET

SIMPLE SUMMARY: Medullary thyroid carcinoma (MTC) is a rare neoplasm supported by a strong genetic determinism. This review summarizes the genetic landscape of MTC at both germline and somatic levels to understand the molecular basis and the natural history of the tumour, mainly but not exclusively,...

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Detalles Bibliográficos
Autores principales: Sahakian, Nicolas, Castinetti, Frédéric, Romanet, Pauline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572078/
https://www.ncbi.nlm.nih.gov/pubmed/37835559
http://dx.doi.org/10.3390/cancers15194865