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NAD(+) Acts as a Protective Factor in Cellular Stress Response to DNA Alkylating Agents
Sulfur mustard (SM) and its derivatives are potent genotoxic agents, which have been shown to trigger the activation of poly (ADP-ribose) polymerases (PARPs) and the depletion of their substrate, nicotinamide adenine dinucleotide (NAD(+)). NAD(+) is an essential molecule involved in numerous cellula...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572126/ https://www.ncbi.nlm.nih.gov/pubmed/37830610 http://dx.doi.org/10.3390/cells12192396 |