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NAD(+) Acts as a Protective Factor in Cellular Stress Response to DNA Alkylating Agents

Sulfur mustard (SM) and its derivatives are potent genotoxic agents, which have been shown to trigger the activation of poly (ADP-ribose) polymerases (PARPs) and the depletion of their substrate, nicotinamide adenine dinucleotide (NAD(+)). NAD(+) is an essential molecule involved in numerous cellula...

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Detalles Bibliográficos
Autores principales: Ruszkiewicz, Joanna, Papatheodorou, Ylea, Jäck, Nathalie, Melzig, Jasmin, Eble, Franziska, Pirker, Annika, Thomann, Marius, Haberer, Andreas, Rothmiller, Simone, Bürkle, Alexander, Mangerich, Aswin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572126/
https://www.ncbi.nlm.nih.gov/pubmed/37830610
http://dx.doi.org/10.3390/cells12192396