Prolonged Inhibition of the MEK1/2-ERK Signaling Axis Primes Interleukin-1 Beta Expression through Histone 3 Lysine 9 Demethylation in Murine Macrophages

Macrophages undergo different cellular states upon activation that can be hyporesponsive (tolerated) or hyperresponsive (primed or trained) to subsequent stimuli. Epigenetic modifications are known to play key roles in determining these cellular states. However, little is known about the role of sig...

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Detalles Bibliográficos
Autores principales: Low, Rachel, Ha, Soon-Duck, Sleapnicov, Nichita, Maneesh, Parthiv, Kim, Sung Ouk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572145/
https://www.ncbi.nlm.nih.gov/pubmed/37833877
http://dx.doi.org/10.3390/ijms241914428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10572145/
https://www.ncbi.nlm.nih.gov/pubmed/37833877
http://dx.doi.org/10.3390/ijms241914428

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